A Family Approach to Services and Transitions for Opioid Use & Exposure
Mental health conditions, including drug-related overdose deaths and suicides, are the top cause of pregnancy-related deaths in Pennsylvania, contributing to 34% of deaths in 2021. The highest risk occurs in the postpartum period. The Maternal Mortality Review Committee (MMRC) also identified substance use disorder (SUD) contributed to 26% of the deaths, and 98% of all deaths were preventable.1
To prevent these deaths, the MMRC recommends that providers screen for SUD and co-occurring disorders, make warm handoff referrals, standardize discharge plans for postpartum individuals with opioid use disorder (OUD) including naloxone prescription and distribution, consult multi-disciplinary care teams specific to SUD at time of admission, provide medications for OUD or ensure adequate treatment from SUD facilities, follow-up with individuals with SUD after discharge, ensure services and appointments are in place with a closed loop referral prior to discharge, ensure equity use and application of a Plans of Safe Care, ensure standard protocols in place to avoid stigma and discrimination for individuals who are suspected of using substances.
For Neonatal Abstinence Syndrome (NAS), the incidence per 1,000 live births in 2023 was 9.1—a decrease from the 2022 rate of 9.6. In regard to the discharge plan and referrals for those with NAS, 62% had a Plan of Safe Care initiated, 31% were referred to Early Intervention, 11% were referred to home visiting services, and 51% were referred to pediatricians experienced with NAS, among other referrals. PA DOH’s NAS report describes the opportunity to improve awareness and education of hospital providers on available services and the importance of coordinated follow-up and referral.2
Sources
1 PA Maternal Mortality Review 2021 Case Data Infographic. PA Department of Health. https://www.pa.gov/content/dam/copapwp-pagov/en/health/documents/topics/documents/programs/2025%20Pennsylvania%20Maternal%20Mortality%20Review%20Infographic%E2%80%8B.pdf. October 16, 2025.
*2025 PA Maternal Mortality Review Annual Report, Deaths occurring in 2021 (Full Report). https://www.pa.gov/content/dam/copapwp-pagov/en/health/documents/topics/documents/programs/2025%20MMR%20Report.pdf. August 2025.
2 Neonatal Abstinence Syndrome: 2023 Report Bureau of Family Health and Bureau of Epidemiology April 2025. https://www.pa.gov/content/dam/copapwp-pagov/en/health/documents/topics/documents/opioids/NAS%202023%20Annual%20Report.pdf
